International Stem Cell Corporation Developed 3D Bioprinting Technology Targeted to Treat Liver Diseases
The International Stem Cell Corporation (ISCO) (OTCQB:ISCO), a clinical stage biotechnology company based in California, has announced the development of a new 3D bioprinter that produces liver tissue.
The technology is suited to the liver progenitor cell (LPC) line, adding to ISCO’s existing pipeline of products including ISC-hpNSC for brain treatments, and ChondraStem to treat osteoarthritis.
ISC-hpNSC’s therapeutic use for Parkinson’s Disease is in Phase I clinical trails, making it ISCO’s closest line to market. Liver cells, by comparison, are still in the basic research stage, meaning 3D bioprinting could prove invaluable to progress.
ISCO’s R&D team has developed a 3D bioprinter which utilizes proprietary liver progenitor cells (LPC), which differentiate into cholangiocytes, hepatocytes and stellate cells. Once 3D liver-like structures are produced from the LPC, they are expected to provide a treatment for various liver diseases once transplanted into the damaged liver. The LPC can be derived from any kind of pluripotent stem cells, including human embryonic, induced pluripotent, or parthenogenetic stem cells, via ISCO’s proprietary highly efficient and scalable differentiation method.
“I’m excited to announce that we have developed a new efficient technology to produce 3D liver tissue, which may be able to replace damaged tissue to restore liver functions. Additionally, the developed liver tissue potentially can be used not only in liver treatment, but also in drug discovery as a model for drug screening, which opens up a potential multi-billion market for ISCO” commented Russell Kern, PhD., Executive Vice President and Chief Scientific Officer of ISCO.
“We have already developed a master cell bank of the liver progenitor cells and, we are proceeding to test safety and efficacy of the cells in various models of liver diseases like liver cirrhosis and fibrosis” he continued.
3D printing has the ability to save lives, and it’s stories like this that should inspire you to utilize the industry and technology we have to make life better for everyone.
From little things such as water bottle holders on wheelchairs, all the way up to 3D printed organs, the possibilities are endless and only with your determination and ability to inspire the classroom will we see progress in this ever-growing field.
For more information visit ISCO’s official website to see some more of the amazing work they do, and who knows, maybe you’ll inspire someone with this story!
Thank you for reading, see you next time.
“International Stem Cell Corporation (ISCO) is a publicly traded clinical stage biotechnology company with a powerful new stem cell technology called human parthenogenetic activation that promises to significantly advance the field of regenerative medicine.”